Retinoic Acid Receptor Gamma (RARγ) Promotes Cartilage Destruction through Positive Feedback Activation of NF-κB Pathway in Human Osteoarthritis

• Main Authors: Yue-Wei Yu (Author), Si-Yang Li (Author), Lin-Jun Zhang (Author), Qian-Liang Wang (Author), Zhong-Guo Liu (Author), Qing-Zhi Chen (Author), Hong-Yu Song (Author), Dong-Yan Shen (Author), Jun Yan (Author)
• Format: Book
• Published: Hindawi Limited, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Osteoarthritis (OA) is a severe inflammation-related disease which leads to cartilage destruction. The retinoic acid receptor gamma (RARγ) has been indicated to be involved in many inflammation processes. However, the role and mechanism of RARγ in cartilage destruction caused by inflammation in OA a...