The Involvement of Renin-Angiotensin System in Lipopolysaccharide-Induced Behavioral Changes, Neuroinflammation, and Disturbed Insulin Signaling

• Main Authors: Xiaoxue Gong (Author), Hui Hu (Author), Yi Qiao (Author), Pengfei Xu (Author), Mengqi Yang (Author), Ruili Dang (Author), Wenxiu Han (Author), Yujin Guo (Author), Dan Chen (Author), Pei Jiang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Brain insulin signaling is accounted for the development of a variety of neuropsychiatric disorders, such as anxiety and depression, whereas both inflammation and the activated renin-angiotensin system (RAS) are two major contributors to insulin resistance. Intriguingly, inflammation and RAS can act...