Synthesis of Novel <i>N</i>⁴-Hydrocytidine Analogs as Potential Anti-SARS-CoV-2 Agents

• Main Authors: Franck Amblard (Author), Julia C. LeCher (Author), Ramyani De (Author), Shu Ling Goh (Author), Chengwei Li (Author), Mahesh Kasthuri (Author), Nicolas Biteau (Author), Longhu Zhou (Author), Zahira Tber (Author), Jessica Downs-Bowen (Author), Keivan Zandi (Author), Raymond F. Schinazi (Author)
• Format: Book
• Published: MDPI AG, 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Coronavirus disease 2019 (COVID-19) is an emerging global pandemic with severe morbidity and mortality caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Molnupiravir, an ester prodrug form of <i>N</i>⁴-hydroxycytidine (NHC), was recently e...