In vivo screening for toxicity-modulating drug interactions identifies antagonism that protects against ototoxicity in zebrafish

• 主要な著者: Ethan Bustad (著者), Emma Mudrock (著者), Elizabeth M. Nilles (著者), Andrea Mcquate (著者), Monica Bergado (著者), Alden Gu (著者), Louie Galitan (著者), Natalie Gleason (著者), Henry C. Ou (著者), David W. Raible (著者), Rafael E. Hernandez (著者), Shuyi Ma (著者)
• フォーマット: 図書
• 出版事項: Frontiers Media S.A., 2024-03-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Introduction: Ototoxicity is a debilitating side effect of over 150 medications with diverse mechanisms of action, many of which could be taken concurrently to treat multiple conditions. Approaches for preclinical evaluation of drug-drug interactions that might impact ototoxicity would facilitate de...