Obg-Like ATPase 1 Enhances Chemoresistance of Breast Cancer via Activation of TGF-β/Smad Axis Cascades

• Main Authors: Jianzhou Liu (Author), Xiaoyu Miao (Author), Bowen Xiao (Author), Jing Huang (Author), Xufeng Tao (Author), Jiong Zhang (Author), Hua Zhao (Author), Yue Pan (Author), Hongwei Wang (Author), Ge Gao (Author), Gary Guishan Xiao (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Understanding the molecular mechanism of drug resistance helps to identify an effective target for breast cancer therapy. In this study we investigated the regulatory role of Obg-like ATPase 1 which is involved in multiple uses of drug resistance against breast cancer. Paclitaxel resistant cell line...