A Unique Core-Shell Structured, Glycol Chitosan-Based Nanoparticle Achieves Cancer-Selective Gene Delivery with Reduced Off-Target Effects

The inherent instability of nucleic acids within serum and the tumor microenvironment necessitates a suitable vehicle for non-viral gene delivery to malignant lesions. A specificity-conferring mechanism is also often needed to mitigate off-target toxicity. In the present study, we report a stable an...

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Príomhchruthaitheoirí: Bei Cheng (Údar), Hye-Hyun Ahn (Údar), Hwanhee Nam (Údar), Zirui Jiang (Údar), Feng J. Gao (Údar), Il Minn (Údar), Martin G. Pomper (Údar)
Formáid: LEABHAR
Foilsithe / Cruthaithe: MDPI AG, 2022-02-01T00:00:00Z.
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