Study of influence of Catha edulis (Khat) chewing on oral pharmacokinetics of irbesartan in rats using a newly developed HPLC-UV method

• Main Authors: Hassan A. Alhazmi (Author), Mustafa A. Bakri (Author), Yahya A. Mohzari (Author), Yousef G. Alshigaify (Author), Mohammed Al Bratty (Author), Sadique A. Javed (Author), Asim Najmi (Author), Ziaur Rehman (Author), Waquar Ahsan (Author), Manal Mohamed Elhassan Taha (Author)
• Format: Book
• Published: Elsevier, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Khat consumers might use a number of drugs for underlying conditions; however the potential drug-herb interaction between khat and other drugs including Irbesartan (IRB) is unknown. The present study was conducted to evaluate the effects of khat chewing on pharmacokinetic profile of IRB, a commonly...