Modelling the Evolution of Pore Structure during the Disintegration of Pharmaceutical Tablets

• Main Authors: Mithushan Soundaranathan (Author), Mohammed Al-Sharabi (Author), Thomas Sweijen (Author), Prince Bawuah (Author), J. Axel Zeitler (Author), S. Majid Hassanizadeh (Author), Kendal Pitt (Author), Blair F. Johnston (Author), Daniel Markl (Author)
• Format: Book
• Published: MDPI AG, 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pharmaceutical tablet disintegration is a critical process for dissolving and enabling the absorption of the drug substance into the blood stream. The tablet disintegration process consists of multiple connected and interdependent mechanisms: liquid penetration, swelling, dissolution, and break-up....