Prevalent levels of RSV serum neutralizing antibodies in healthy adults outside the RSV-season

• Автори: Johan L. Van Der Plas (Автор), Pauline Verdijk (Автор), Emilie M. J. Van Brummelen (Автор), Rienk E. Jeeninga (Автор), Meta Roestenberg (Автор), Jacobus Burggraaf (Автор), Ingrid M.C. Kamerling (Автор)
• Формат: Книга
• Опубліковано: Taylor & Francis Group, 2020-06-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

One of the main challenges in early clinical research with respiratory syncytial virus (RSV) live-attenuated vaccines (LAVs) is to assess immunogenicity in healthy adults. Healthy adults will have preexisting levels of serum neutralizing antibodies that could prematurely neutralize the LAV and under...