MnTnHex-2-PyP⁵⁺, Coupled to Radiation, Suppresses Metastasis of 4T1 and MDA-MB-231 Breast Cancer via AKT/Snail/EMT Pathways

• Main Authors: Sung-Won Shin (Author), Changhoon Choi (Author), Hakyoung Kim (Author), Yeeun Kim (Author), Sohee Park (Author), Shin-Yeong Kim (Author), Ines Batinic-Haberle (Author), Won Park (Author)
• Format: Book
• Published: MDPI AG, 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Tumor migration and invasion induced by the epithelial-to-mesenchymal transition (EMT) are prerequisites for metastasis. Here, we investigated the inhibitory effect of a mimic of superoxide dismutase (SOD), cationic Mn(III) <i>ortho</i>-substituted <i>N</i>-n-hexylpyridylporp...