Developing patient-derived organoids to demonstrate JX24120 inhibits SAMe synthesis in endometrial cancer by targeting MAT2B

• Главные авторы: Chunxue Zhang (Автор), Xiaojing Lu (Автор), Ting Ni (Автор), Qi Wang (Автор), Xiaoyan Gao (Автор), Xiao Sun (Автор), Jian Li (Автор), Fei Mao (Автор), Jin Hou (Автор), Yudong Wang (Автор)
• Формат: ‌
• Опубликовано: Elsevier, 2024-11-01T00:00:00Z.
• Предметы: article
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Endometrial cancer (EC) is one of the most common gynecologic malignancies, which lacking effective drugs for intractable conditions or patients unsuitable for surgeries. Recently, the patient-derived organoids (PDOs) are found feasible for cancer research and drug discoveries. Here, we have success...