Identification of Mepenzolate Derivatives With Long-Acting Bronchodilatory Activity

Identification of Mepenzolate Derivatives With Long-Acting Bronchodilatory Activity

The standard treatment for chronic obstructive pulmonary disease is a combination of anti-inflammatory drugs and bronchodilators. We recently found that mepenzolate bromide (MP), an antagonist for human muscarinic M3 receptor (hM3R), has both anti-inflammatory and short-acting bronchodilatory activi...

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Main Authors: Ken-Ichiro Tanaka (Author), Naoki Yamakawa (Author), Yasunobu Yamashita (Author), Teita Asano (Author), Yuki Kanda (Author), Ayaka Takafuji (Author), Masahiro Kawahara (Author), Mitsuko Takenaga (Author), Yoshifumi Fukunishi (Author), Tohru Mizushima (Author)
Format: Book
Published: Frontiers Media S.A., 2018-04-01T00:00:00Z.
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