Development and Evaluation of a Physiologically Based Pharmacokinetic Model of Labetalol in Healthy and Diseased Populations

• Main Authors: Hafsa Hafsa (Author), Ammara Zamir (Author), Muhammad Fawad Rasool (Author), Imran Imran (Author), Hamid Saeed (Author), Tanveer Ahmad (Author), Sary Alsanea (Author), Ali A. Alshamrani (Author), Abdullah H. Alruwaili (Author), Faleh Alqahtani (Author)
• Format: Book
• Published: MDPI AG, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Labetalol is a drug that exhibits both alpha and beta-adrenergic receptor-blocking properties. The American Heart Association/American Stroke Association (AHA/ASA) has recommended labetalol as an initial treatment option for the management of severe hypertension. The physiologically based pharmacoki...