miR-135b Stimulates Osteosarcoma Recurrence and Lung Metastasis via Notch and Wnt/β-Catenin Signaling

• Главные авторы: Hua Jin (Автор), Song Luo (Автор), Yun Wang (Автор), Chang Liu (Автор), Zhenghao Piao (Автор), Meng Xu (Автор), Wei Guan (Автор), Qing Li (Автор), Hua Zou (Автор), Qun-You Tan (Автор), Zhen-Zhou Yang (Автор), Yan Wang (Автор), Dong Wang (Автор), Cheng-Xiong Xu (Автор)
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• Опубликовано: Elsevier, 2017-09-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Cancer stem cells (CSCs) play an important role in osteosarcoma (OS) metastasis and recurrence, and both Wnt/β-catenin and Notch signaling are essential for the development of the biological traits of CSCs. However, the mechanism that underlies the simultaneous hyperactivation of both Wnt/β-catenin...