A double-hit pre-eclampsia model results in sex-specific growth restriction patterns

• Hauptverfasser: Violeta Stojanovska (Verfasst von), Dorieke J. Dijkstra (Verfasst von), Rebekka Vogtmann (Verfasst von), Alexandra Gellhaus (Verfasst von), Sicco A. Scherjon (Verfasst von), Torsten Plösch (Verfasst von)
• Format: Buch
• Veröffentlicht: The Company of Biologists, 2019-02-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Pre-eclampsia is a multifactorial pregnancy-associated disorder characterized by angiogenic dysbalance and systemic inflammation; however, animal models that combine these two pathophysiological conditions are missing. Here, we introduce a novel double-hit pre-eclampsia mouse model that mimics the c...