Cost-Effectiveness of perioperative Vaginally Administered estrogen in postmenopausal women undergoing prolapse surgery (EVA trial): study protocol for a multicenter double-blind randomized placebo-controlled trial

• Main Authors: Eva V. Vodegel (Author), Sandra E. Zwolsman (Author), Astrid Vollebregt (Author), Ruben G. Duijnhoven (Author), Judith E. Bosmans (Author), Leonie Speksnijder (Author), Eveline J. Roos (Author), Wilbert Spaans (Author), Franca Gerards (Author), Albert Adriaanse (Author), Flora Vernooij (Author), Alfredo L. Milani (Author), Marko Sikkema (Author), Mirjam Weemhoff (Author), Marieke Mous (Author), Anne Damoiseaux (Author), Heleen van Dongen (Author), Marinus v/d Ploeg (Author), Joggem Veen (Author), Geerte van de Pol (Author), Bart Broekman (Author), Pieternel Steures (Author), Fernando Tjin-Asjoe (Author), Jolande van der Stege (Author), Ronald Mouw (Author), Carl H. van der Vaart (Author), Jan-Paul W. R. Roovers (Author)
• Format: Book
• Published: BMC, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Surgery for pelvic organ prolapse (POP) is associated with high recurrence rates. The costs associated with the treatment of recurrent POP are huge, and the burden from women who encounter recurrent POP, negatively impacts their quality of life. Estrogen therapy might improve sur...