Synthesis and Evaluation of the Antibacterial Activities of 13-Substituted Berberine Derivatives

• Main Authors: Hamza Olleik (Author), Taher Yacoub (Author), Laurent Hoffer (Author), Senankpon Martial Gnansounou (Author), Kehna Benhaiem-Henry (Author), Cendrine Nicoletti (Author), Malika Mekhalfi (Author), Valérie Pique (Author), Josette Perrier (Author), Akram Hijazi (Author), Elias Baydoun (Author), Josette Raymond (Author), Philippe Piccerelle (Author), Marc Maresca (Author), Maxime Robin (Author)
• Format: Book
• Published: MDPI AG, 2020-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The biological activities of berberine, a natural plant molecule, are known to be affected by structural modifications, mostly at position 9 and/or 13. A series of new 13-substituted berberine derivatives were synthesized and evaluated in term of antimicrobial activity using various microorganisms a...