Identification of Potential JNK3 Inhibitors: A Combined Approach Using Molecular Docking and Deep Learning-Based Virtual Screening

• Main Authors: Chenpeng Yao (Author), Zheyuan Shen (Author), Liteng Shen (Author), Kailibinuer Kadier (Author), Jingyi Zhao (Author), Yu Guo (Author), Lei Xu (Author), Ji Cao (Author), Xiaowu Dong (Author), Bo Yang (Author)
• Format: Book
• Published: MDPI AG, 2023-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

JNK3, a member of the MAPK family, plays a pivotal role in mediating cellular responses to stress signals, with its activation implicated in a myriad of inflammatory conditions. While JNK3 holds promise as a therapeutic target for neurodegenerative disorders such as Huntington's, Parkinson'...