Liver metabolomics reveals potential mechanism of Jieduan-Niwan formula against acute-on-chronic liver failure (ACLF) by improving mitochondrial damage and TCA cycle

• Autores principales: Jiajun Liang (Autor), Xiaoyi Wei (Autor), Weixin Hou (Autor), Hanjing Wang (Autor), Ruimin Ma (Autor), Yanbin Gao (Autor), Yuqiong Du (Autor), Qiuyun Zhang (Autor)
• Formato: Libro
• Publicado: BMC, 2023-11-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Abstract Background Acute-on-chronic liver failure (ACLF) is a refractory disease with high mortality, which is characterized by a pathophysiological process of inflammation-related dysfunction of energy metabolism. Jieduan-Niwan formula (JDNWF) is a eutherapeutic Chinese medicine formula for ACLF....