Liver metabolomics reveals potential mechanism of Jieduan-Niwan formula against acute-on-chronic liver failure (ACLF) by improving mitochondrial damage and TCA cycle

• Main Authors: Jiajun Liang (Author), Xiaoyi Wei (Author), Weixin Hou (Author), Hanjing Wang (Author), Ruimin Ma (Author), Yanbin Gao (Author), Yuqiong Du (Author), Qiuyun Zhang (Author)
• Format: Book
• Published: BMC, 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Acute-on-chronic liver failure (ACLF) is a refractory disease with high mortality, which is characterized by a pathophysiological process of inflammation-related dysfunction of energy metabolism. Jieduan-Niwan formula (JDNWF) is a eutherapeutic Chinese medicine formula for ACLF....