An optimized color transformation for the analysis of digital images of hematoxylin & eosin stained slides

• Main Authors: Mark D Zarella (Author), David E Breen (Author), Andrei Plagov (Author), Fernando U Garcia (Author)
• Format: Book
• Published: Elsevier, 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hematoxylin and eosin (H&E) staining is ubiquitous in pathology practice and research. As digital pathology has evolved, the reliance of quantitative methods that make use of H&E images has similarly expanded. For example, cell counting and nuclear morphometry rely on the accurate demarcatio...