Association Between Genetic Polymorphisms of the β1-Adrenergic Receptor and Sensitivity to Pain and Fentanyl in Patients Undergoing Painful Cosmetic Surgery

• Main Authors: Ayako Moriyama (Author), Daisuke Nishizawa (Author), Shinya Kasai (Author), Junko Hasegawa (Author), Ken-ichi Fukuda (Author), Makoto Nagashima (Author), Ryoji Katoh (Author), Kazutaka Ikeda (Author)
• Format: Book
• Published: Elsevier, 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Individual differences in the sensitivity to fentanyl, a widely used opioid analgesic, can hamper effective pain treatment. The adrenergic system is reportedly involved in the mechanisms of pain and analgesia. Here, we focused on one of the adrenergic receptor genes, ADRB1, and analyzed the influenc...