New Synthesis, Structure and Analgesic Properties of Methyl 1-R-4-Methyl-2,2-Dioxo-1H-2λ6,1-Benzothiazine-3-Carboxylates

• Main Authors: Liliana Azotla-Cruz (Author), Irina V. Lijanova (Author), Igor V. Ukrainets (Author), Natalya V. Likhanova (Author), Octavio Olivares-Xometl (Author), Natalya L. Bereznyakova (Author)
• Format: Book
• Published: MDPI AG, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

According to the principles of the methodology of bioisosteric replacements a series of methyl 1-R-4-methyl-2,2-dioxo-1H-2λ6,1-benzothiazine-3-carboxylates has been obtained as potential analgesics. In addition, a fundamentally new strategy for the synthesis of compounds of this chemical class invol...