Optimization of Cholinesterase-Based Catalytic Bioscavengers Against Organophosphorus Agents

Optimization of Cholinesterase-Based Catalytic Bioscavengers Against Organophosphorus Agents

Organophosphorus agents (OPs) are irreversible inhibitors of acetylcholinesterase (AChE). OP poisoning causes major cholinergic syndrome. Current medical counter-measures mitigate the acute effects but have limited action against OP-induced brain damage. Bioscavengers are appealing alternative thera...

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Main Authors: Sofya V. Lushchekina (Author), Lawrence M. Schopfer (Author), Bella L. Grigorenko (Author), Alexander V. Nemukhin (Author), Sergei D. Varfolomeev (Author), Oksana Lockridge (Author), Patrick Masson (Author)
Format: Book
Published: Frontiers Media S.A., 2018-03-01T00:00:00Z.
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3rd Floor Main Library

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