Sequential waves of gene expression in patients with clinically defined dengue illnesses reveal subtle disease phases and predict disease severity.

• Main Authors: Peifang Sun (Author), Josefina García (Author), Guillermo Comach (Author), Maryanne T Vahey (Author), Zhining Wang (Author), Brett M Forshey (Author), Amy C Morrison (Author), Gloria Sierra (Author), Isabel Bazan (Author), Claudio Rocha (Author), Stalin Vilcarromero (Author), Patrick J Blair (Author), Thomas W Scott (Author), Daria E Camacho (Author), Christian F Ockenhouse (Author), Eric S Halsey (Author), Tadeusz J Kochel (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND: Dengue virus (DENV) infection can range in severity from mild dengue fever (DF) to severe dengue hemorrhagic fever (DHF) or dengue shock syndrome (DSS). Changes in host gene expression, temporally through the progression of DENV infection, especially during the early days, remains poorly...