Sequential waves of gene expression in patients with clinically defined dengue illnesses reveal subtle disease phases and predict disease severity.

• Главные авторы: Peifang Sun (Автор), Josefina García (Автор), Guillermo Comach (Автор), Maryanne T Vahey (Автор), Zhining Wang (Автор), Brett M Forshey (Автор), Amy C Morrison (Автор), Gloria Sierra (Автор), Isabel Bazan (Автор), Claudio Rocha (Автор), Stalin Vilcarromero (Автор), Patrick J Blair (Автор), Thomas W Scott (Автор), Daria E Camacho (Автор), Christian F Ockenhouse (Автор), Eric S Halsey (Автор), Tadeusz J Kochel (Автор)
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• Опубликовано: Public Library of Science (PLoS), 2013-01-01T00:00:00Z.
• Предметы: article
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BACKGROUND: Dengue virus (DENV) infection can range in severity from mild dengue fever (DF) to severe dengue hemorrhagic fever (DHF) or dengue shock syndrome (DSS). Changes in host gene expression, temporally through the progression of DENV infection, especially during the early days, remains poorly...