Predicting the Release Mechanism of Amorphous Solid Dispersions: A Combination of Thermodynamic Modeling and In Silico Molecular Simulation

Predicting the Release Mechanism of Amorphous Solid Dispersions: A Combination of Thermodynamic Modeling and In Silico Molecular Simulation

Background: During the dissolution of amorphous solid dispersion (ASD) formulations, the drug load (DL) often impacts the release mechanism and the occurrence of loss of release (LoR). The ASD/water interfacial gel layer and its specific phase behavior in connection with DL strongly dictate the rele...

Full description

Saved in:
Bibliographic Details
Main Authors: Stefanie Walter (Author), Paulo G. M. Mileo (Author), Mohammad Atif Faiz Afzal (Author), Samuel O. Kyeremateng (Author), Matthias Degenhardt (Author), Andrea R. Browning (Author), John C. Shelley (Author)
Format: Book
Published: MDPI AG, 2024-10-01T00:00:00Z.
Subjects:
article
Online Access:Connect to this object online.
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

Connect to this object online.

3rd Floor Main Library

Holdings details from 3rd Floor Main Library
Call Number: A1234.567
Copy 1 Available

Similar Items