Autophagy, Oxidative Stress, and Alcoholic Liver Disease: A Systematic Review and Potential Clinical Applications

• Main Authors: Daniel Salete-Granado (Author), Cristina Carbonell (Author), David Puertas-Miranda (Author), Víctor-Jos (Author), Marina García-Macia (Author), Ana Belén Herrero (Author), Miguel Marcos (Author)
• Format: Book
• Published: MDPI AG, 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ethanol consumption triggers oxidative stress by generating reactive oxygen species (ROS) through its metabolites. This process leads to steatosis and liver inflammation, which are critical for the development of alcoholic liver disease (ALD). Autophagy is a regulated dynamic process that sequesters...