Targeting glycolysis in non-small cell lung cancer: Promises and challenges

• Principais autores: Jia-Qi Xu (Autor), Yan-Li Fu (Autor), Jing Zhang (Autor), Kai-Yu Zhang (Autor), Jie Ma (Autor), Jing-Yi Tang (Autor), Zhi-Wei Zhang (Autor), Zhong-Yan Zhou (Autor)
• Formato: Livro
• Publicado em: Frontiers Media S.A., 2022-11-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Metabolic disturbance, particularly of glucose metabolism, is a hallmark of tumors such as non-small cell lung cancer (NSCLC). Cancer cells tend to reprogram a majority of glucose metabolism reactions into glycolysis, even in oxygen-rich environments. Although glycolysis is not an efficient means of...