Impairment of aryl hydrocarbon receptor signalling promotes hepatic disorders in cancer cachexia

• Main Authors: Adeline Dolly (Author), Sarah A. Pötgens (Author), Morgane M. Thibaut (Author), Audrey M. Neyrinck (Author), Gabriela S. deCastro (Author), Chloé Galbert (Author), Camille Lefevre (Author), Elisabeth Wyart (Author), Silvio P. Gomes (Author), Daniela C. Gonçalves (Author), Nicolas Lanthier (Author), Pamela Baldin (Author), Joshua R. Huot (Author), Andrea Bonetto (Author), Marília Seelaender (Author), Nathalie M. Delzenne (Author), Harry Sokol (Author), Laure B. Bindels (Author)
• Format: Book
• Published: Wiley, 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The aryl hydrocarbon receptor (AHR) is expressed in the intestine and liver, where it has pleiotropic functions and target genes. This study aims to explore the potential implication of AHR in cancer cachexia, an inflammatory and metabolic syndrome contributing to cancer death. S...