Gabapentin-Induced Adrenal Insufficiency: The Hypothalamic-Pituitary-Adrenal Axis Stress Misresponse and Risk of Infection: A Case Report and Literature Review

• Main Authors: Evmorfia Pechlivanidou (Author), Alexandros Chatzikyriakos (Author), Maria Anna Zisi (Author), Nikolaos Paraskevopoulos (Author), Semeli Kaltsa (Author), Orestis K. Konstantas (Author), Panteleimon Zogakis (Author), Aikaterini Catsouli (Author), Nick Sekouris (Author), Rodanthi E. Margariti (Author)
• Format: Book
• Published: MDPI AG, 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This literature review, in light of the presented case report, explores the complex interplay between gabapentin (GBP), a gamma-aminobutyric acid (GABA) analog, and the hypothalamic-pituitary-adrenal (HPA) axis in patients undergoing major surgical procedures. It specifically investigates the potent...