Effects of the Glass-Forming Ability and Annealing Conditions on Cocrystallization Behaviors via Rapid Solvent Removal: A Case Study of Voriconazole

• Main Authors: Si Nga Wong (Author), Susan Wing Sze Chan (Author), Xuexin Peng (Author), Bianfei Xuan (Author), Hok Wai Lee (Author), Henry H. Y. Tong (Author), Shing Fung Chow (Author)
• Format: Book
• Published: MDPI AG, 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The kinetic entrapment of molecules in an amorphous phase is a common obstacle to cocrystal screening using rapid solvent removal, especially for drugs with a moderate or high glass-forming ability (GFA). The aim of this study was to elucidate the effects of the coformer's GFA and annealing con...