Synthesis and biological evaluation of certain hydrazonoindolin-2-one derivatives as new potent anti-proliferative agents

• Main Authors: Wagdy M. Eldehna (Author), Reem I. Al-Wabli (Author), Maha S. Almutairi (Author), Adam B. Keeton (Author), Gary A. Piazza (Author), Hatem A. Abdel-Aziz (Author), Mohamed I. Attia (Author)
• Format: Book
• Published: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In connection with our research program on the development of novel indolin-2-one-based anticancer candidates, herein we report the design and synthesis of different series of hydrazonoindolin-2-ones 3a-e, 5a-e, 7a-c, and 10a-l. The synthesised derivatives were in vitro evaluated for their anti-prol...