Evaluation of the imputation performance of the program IMPUTE in an admixed sample from Mexico City using several model designs

• Main Authors: Krithika S (Author), Valladares-Salgado Adán (Author), Peralta Jesus (Author), La Peña Jorge (Author), Kumate-Rodríguez Jesus (Author), Cruz Miguel (Author), Parra Esteban J (Author)
• Format: Book
• Published: BMC, 2012-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>We explored the imputation performance of the program IMPUTE in an admixed sample from Mexico City. The following issues were evaluated: (a) the impact of different reference panels (HapMap vs. 1000 Genomes) on imputation; (b) potent...