Evaluation of the imputation performance of the program IMPUTE in an admixed sample from Mexico City using several model designs

• Auteurs principaux: Krithika S (Auteur), Valladares-Salgado Adán (Auteur), Peralta Jesus (Auteur), La Peña Jorge (Auteur), Kumate-Rodríguez Jesus (Auteur), Cruz Miguel (Auteur), Parra Esteban J (Auteur)
• Format: Livre
• Publié: BMC, 2012-05-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>We explored the imputation performance of the program IMPUTE in an admixed sample from Mexico City. The following issues were evaluated: (a) the impact of different reference panels (HapMap vs. 1000 Genomes) on imputation; (b) potent...