Micro Injection Molding of Drug-Loaded Round Window Niche Implants for an Animal Model Using 3D-Printed Molds

• Main Authors: Robert Mau (Author), Thomas Eickner (Author), Gábor Jüttner (Author), Ziwen Gao (Author), Chunjiang Wei (Author), Nicklas Fiedler (Author), Volkmar Senz (Author), Thomas Lenarz (Author), Niels Grabow (Author), Verena Scheper (Author), Hermann Seitz (Author)
• Format: Book
• Published: MDPI AG, 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A novel approach for the long-term medical treatment of the inner ear is the diffusion of drugs through the round window membrane from a patient-individualized, drug-eluting implant, which is inserted in the middle ear. In this study, drug-loaded (10 wt% Dexamethasone) guinea pig round window niche...