PAQR9 regulates hepatic ketogenesis and fatty acid oxidation during fasting by modulating protein stability of PPARα

• Main Authors: Yijun Lin (Author), Lingling Chen (Author), Xue You (Author), Zixuan Li (Author), Chenchen Li (Author), Yan Chen (Author)
• 格式: 图书
• 出版: Elsevier, 2021-11-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

Background: The cycle of feeding and fasting is fundamental to life and closely coordinated with changes of metabolic programs. During extended starvation, ketogenesis coupled with fatty acid oxidation in the liver supplies ketone bodies to extrahepatic tissues as the major form of fuel. In this stu...