Protein acetylation in skeletal muscle mitochondria is involved in impaired fatty acid oxidation and exercise intolerance in heart failure

• Главные авторы: Masaya Tsuda (Автор), Arata Fukushima (Автор), Junichi Matsumoto (Автор), Shingo Takada (Автор), Naoya Kakutani (Автор), Hideo Nambu (Автор), Katsuma Yamanashi (Автор), Takaaki Furihata (Автор), Takashi Yokota (Автор), Koichi Okita (Автор), Shintaro Kinugawa (Автор), Toshihisa Anzai (Автор)
• Формат: ‌
• Опубликовано: Wiley, 2018-10-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Abstract Background Exercise intolerance is a common clinical feature and is linked to poor prognosis in patients with heart failure (HF). Skeletal muscle dysfunction, including impaired energy metabolism in the skeletal muscle, is suspected to play a central role in this intolerance, but the underl...