A high-throughput phenotypic screen identifies clofazimine as a potential treatment for cryptosporidiosis.

• Main Authors: Melissa S Love (Author), Federico C Beasley (Author), Rajiv S Jumani (Author), Timothy M Wright (Author), Arnab K Chatterjee (Author), Christopher D Huston (Author), Peter G Schultz (Author), Case W McNamara (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2017-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cryptosporidiosis has emerged as a leading cause of non-viral diarrhea in children under five years of age in the developing world, yet the current standard of care to treat Cryptosporidium infections, nitazoxanide, demonstrates limited and immune-dependent efficacy. Given the lack of treatments wit...