The KCa2 Channel Inhibitor AP30663 Selectively Increases Atrial Refractoriness, Converts Vernakalant-Resistant Atrial Fibrillation and Prevents Its Reinduction in Conscious Pigs

The KCa2 Channel Inhibitor AP30663 Selectively Increases Atrial Refractoriness, Converts Vernakalant-Resistant Atrial Fibrillation and Prevents Its Reinduction in Conscious Pigs

AimsTo describe the effects of the KCa2 channel inhibitor AP30663 in pigs regarding tolerability, cardiac electrophysiology, pharmacokinetics, atrial functional selectivity, effectiveness in cardioversion of tachy-pacing induced vernakalant-resistant atrial fibrillation (AF), and prevention of reind...

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Main Authors: Jonas Goldin Diness (Author), Jeppe Egedal Kirchhoff (Author), Tobias Speerschneider (Author), Lea Abildgaard (Author), Nils Edvardsson (Author), Ulrik S. Sørensen (Author), Morten Grunnet (Author), Bo Hjorth Bentzen (Author)
Format: Book
Published: Frontiers Media S.A., 2020-02-01T00:00:00Z.
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