Castration-resistant prostate cancer patient presenting with whole genome doubling with CDK-12 mutation

• Main Authors: Yuto Baba (Author), Takeo Kosaka (Author), Hiroaki Kobayashi (Author), Kohei Nakamura (Author), Shuji Mikami (Author), Hiroshi Nishihara (Author), Makoto Nakanishi (Author), Mototsugu Oya (Author)
• Format: Book
• Published: BMC, 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The use of whole-genome sequencing in clinical practice has revealed variable genomic characteristics across cancer types, one of which is whole-genome doubling (WGD), which describes the duplication of a complete set of chromosomes. Yet it is relatively rare in prostate cancer a...