Distribution Evaluation of Tenofovir in the Breast Milk of Mothers With HBeAg-Positive Chronic HBV Infection After Treatment With Tenofovir Alafenamide and Tenofovir Disoproxil Fumarate by a Sensitive UPLC-MS/MS Method

• Main Authors: Na Yang (Author), Guanlun Zhou (Author), Xiaoliang Cheng (Author), Jun He (Author), Yan Chen (Author), Chao Chen (Author), Meijuan Li (Author), Jiajia Ge (Author), Min Wang (Author), Tianqi Zhang (Author), Weihong Ge (Author), Huaijun Zhu (Author), Guorong Han (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Tenofovir alafenamide (TAF) is a novel prodrug of tenofovir (TFV) that has been approved for the treatment of chronic hepatitis B virus (HBV) infection. It has greater plasma stability and more favorable renal safety than tenofovir disoproxil fumarate (TDF), the first approved oral prodrug of TFV. H...