Systematic review of melatonin in cerebral ischemia-reperfusion injury: critical role and therapeutic opportunities

• Main Authors: Chenguang Zhang (Author), Yumei Ma (Author), Yating Zhao (Author), Na Guo (Author), Chen Han (Author), Qian Wu (Author), Changqing Mu (Author), Yue Zhang (Author), Shutong Tan (Author), Jian Zhang (Author), Xu Liu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cerebral ischemia-reperfusion (I/R) injury is the predominant causes for the poor prognosis of ischemic stroke patients after reperfusion therapy. Currently, potent therapeutic interventions for cerebral I/R injury are still very limited. Melatonin, an endogenous hormone, was found to be valid in pr...