Clinical Performance of Paraoxonase-1-Related Variables and Novel Markers of Inflammation in Coronavirus Disease-19. A Machine Learning Approach

• Main Authors: Elisabet Rodríguez-Tomàs (Author), Simona Iftimie (Author), Helena Castañé (Author), Gerard Baiges-Gaya (Author), Anna Hernández-Aguilera (Author), María González-Viñas (Author), Antoni Castro (Author), Jordi Camps (Author), Jorge Joven (Author)
• Format: Book
• Published: MDPI AG, 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

SARS-CoV-2 infection produces a response of the innate immune system causing oxidative stress and a strong inflammatory reaction termed 'cytokine storm' that is one of the leading causes of death. Paraoxonase-1 (PON1) protects against oxidative stress by hydrolyzing lipoperoxides. Alterati...