Superficial Dsg2 Expression Limits Epidermal Blister Formation Mediated by Pemphigus Foliaceus Antibodies and Exfoliative Toxins

• Auteurs principaux: Donna Brennan (Auteur), Ying Hu (Auteur), Walid Medhat (Auteur), Alicia Dowling (Auteur), Mỹ G. Mahoney (Auteur)
• Format: Livre
• Publié: Hindawi Limited, 2010-01-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Cell-cell adhesion mediated by desmosomes is crucial for maintaining proper epidermal structure and function, as evidenced by several severe and potentially fatal skin disorders involving impairment of desmosomal proteins. Pemphigus foliaceus (PF) and staphylococcal scalded skin syndrome (SSSS) are...