Defective insulin secretory response to intravenous glucose in C57Bl/6J compared to C57Bl/6N mice

• Үндсэн зохиолчид: Grace Fergusson (Зохиогч), Mélanie Éthier (Зохиогч), Mélanie Guévremont (Зохиогч), Chloé Chrétien (Зохиогч), Camille Attané (Зохиогч), Erik Joly (Зохиогч), Xavier Fioramonti (Зохиогч), Marc Prentki (Зохиогч), Vincent Poitout (Зохиогч), Thierry Alquier (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Elsevier, 2014-12-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Objective: The C57Bl/6J (Bl/6J) mouse is the most widely used strain in metabolic research. This strain carries a mutation in nicotinamide nucleotide transhydrogenase (Nnt), a mitochondrial enzyme involved in NADPH production, which has been suggested to lead to glucose intolerance and beta-cell dys...