In Silico Screening and Validation of PDGFRA Inhibitors Enhancing Radioiodine Sensitivity in Thyroid Cancer

• المؤلفون الرئيسيون: Xuefei Yu (مؤلف), Xuhang Zhu (مؤلف), Lizhuo Zhang (مؤلف), Jiang-Jiang Qin (مؤلف), Chunlai Feng (مؤلف), Qinglin Li (مؤلف)
• التنسيق: كتاب
• منشور في: Frontiers Media S.A., 2022-05-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Aberrant activation of platelet-derived growth factor receptor α (PDGFRA) has been implicated in tumorigenesis and radioiodine resistance of thyroid cancer, indicating its therapeutic potential. In the present study, we confirmed the association between PDGFRA and radioiodine resistance in thyroid c...