Development and validation of a diagnostic model for early differentiation of sepsis and non-infectious SIRS in critically ill children - a data-driven approach using machine-learning algorithms

• Main Authors: Florian Lamping (Author), Thomas Jack (Author), Nicole Rübsamen (Author), Michael Sasse (Author), Philipp Beerbaum (Author), Rafael T. Mikolajczyk (Author), Martin Boehne (Author), André Karch (Author)
• Format: Book
• Published: BMC, 2018-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Since early antimicrobial therapy is mandatory in septic patients, immediate diagnosis and distinction from non-infectious SIRS is essential but hampered by the similarity of symptoms between both entities. We aimed to develop a diagnostic model for differentiation of sepsis and...