Application of physiologically based biopharmaceutics modeling to understand the impact of dissolution differences on in vivo performance of immediate release products: The case of bisoprolol
Abstract Merck KGaA observed slight differences in the dissolution of Concor® (bisoprolol) batches over the years. The purpose of this work was to assess the impact of in vitro dissolution on the simulated pharmacokinetics of bisoprolol using in vitro-in vivo relationship established with available...
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| Main Authors: | , , , , |
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| Format: | Book |
| Published: |
Wiley,
2021-06-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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