Oxaliplatin administration increases expression of the voltage-dependent calcium channel α2δ-1 subunit in the rat spinal cord

• Hlavní autoři: Ken Yamamoto (Autor), Mayuko Tsuboi (Autor), Toshie Kambe (Autor), Kenji Abe (Autor), Yoshihiko Nakatani (Autor), Kazuyoshi Kawakami (Autor), Iku Utsunomiya (Autor), Kyoji Taguchi (Autor)
• Médium: Kniha
• Vydáno: Elsevier, 2016-02-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

Oxaliplatin is a chemotherapeutic agent that is effective against various types of cancer including colorectal cancer. Acute cold hyperalgesia is a serious side effect of oxaliplatin treatment. Although the therapeutic drug pregabalin is beneficial for preventing peripheral neuropathic pain by targe...