Amphiregulin Induces iNOS and COX-2 Expression through NF-κB and MAPK Signaling in Hepatic Inflammation

• Main Authors: Yu Jung Heo (Author), Nami Lee (Author), Sung-E. Choi (Author), Ja Young Jeon (Author), Seung Jin Han (Author), Dae Jung Kim (Author), Yup Kang (Author), Kwan Woo Lee (Author), Hae Jin Kim (Author)
• Format: Book
• Published: Hindawi Limited, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background. Inflammation is a major cause of hepatic tissue damage and accelerates the progression of nonalcoholic fatty liver disease (NAFLD). Amphiregulin (AREG), an epidermal growth factor receptor ligand, is associated with human liver cirrhosis and hepatocellular carcinoma. We aimed to investig...