Voltage-dependent anion channel (VDAC) is involved in apoptosis of cell lines carrying the mitochondrial DNA mutation

• Main Authors: Mohan Liu (Author), Rui Chen (Author), Lin Wang (Author), Hua Xu (Author), Zongbin Li (Author), Yang Li (Author), Lei Gao (Author), Yuqi Liu (Author), Yi Wen (Author), Minxin Guan (Author), Shiwen Wang (Author)
• Format: Book
• Published: BMC, 2009-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>The mitochondrial voltage-dependent anion channel (VDAC) is increasingly implicated in the control of apoptosis. We have studied the effects the mitochondrial DNA (mtDNA) tRNA^Ilemutation on VDAC expression, lo...