Gigantol inhibits Wnt/β-catenin signaling and exhibits anticancer activity in breast cancer cells

• Main Authors: Shubin Yu (Author), Zhongyuan Wang (Author), Zijie Su (Author), Jiaxing Song (Author), Liang Zhou (Author), Qi Sun (Author), Shanshan Liu (Author), Shiyue Li (Author), Ying Li (Author), Meina Wang (Author), Guo-Qiang Zhang (Author), Xue Zhang (Author), Zhong-Jian Liu (Author), Desheng Lu (Author)
• Format: Book
• Published: BMC, 2018-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Gigantol is a bibenzyl compound derived from several medicinal orchids. This biologically active compound has been shown to have promising therapeutic potential against cancer cells, but its mechanism of action remains unclear. Methods The inhibitory effect of gigantol on Wnt/β-c...